Research progress of matrix metalloproteinase-9 in kidney disease / 中国医师杂志
Journal of Chinese Physician
;
(12): 1278-1280,封3, 2017.
Article
Dans Chinois
| WPRIM
| ID: wpr-610842
ABSTRACT
Kidney plays an important role in maintaining the homeostasis as an important excretory and endocrine organ.The occurrence and development of kidney disease is closely associated with glomerular filtration barrier dysfunction and renal interstitial remodeling.Matrix metalloproteinase-9 (MMP-9),a major enzyme in the extracellular matrix (ECM),plays an important role in the process of kidney disease by regulating the ECM components and its interaction with cytokines.The paper reviews the pathophysiology of MMP-9 in glomerular filtration barrier dysfunction and renal fibrosis to provide a theoretical basis for clinical treatment of kidney disease.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Journal of Chinese Physician
Année:
2017
Type:
Article
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