The status quo and future prospects of the next generation sequencing technologies in clinical diagnostics / 中华检验医学杂志
Chinese Journal of Laboratory Medicine
;
(12): 483-485, 2017.
Article
Dans Chinois
| WPRIM
| ID: wpr-611492
ABSTRACT
During the past decade, tremendous progress has been made in terms of speed, read length, and throughput, along with a sharp reduction in per-base cost.Together, these advances democratized next generation sequence (NGS) and paved the way for the development of a large number of novel NGS applications in clinical diagnostics, especially in the field of non-invasive prenatal detection, rare genetic disease and cancer companion diagnostics.As technology advances, long-read single molecule sequencing began to emerge.Single cell, long-reads, transcriptome, and low cost will be the NGS direction.Due to the special nature of clinical testing, the current NGS clinical application system,including genetic counseling, testing standards, quality control, supervision, database construction etc, does not match the national conditions well and still faces a few challenges, needs to be constantly improved through the routine clinical practice in the future.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Type d'étude:
Etude diagnostique
/
Guide de pratique
langue:
Chinois
Texte intégral:
Chinese Journal of Laboratory Medicine
Année:
2017
Type:
Article
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