Role of IL-21 and INF-γ in the pathogenesis of nephrotic syndrome / 国际儿科学杂志

ABSTRACT

The etiology and pathogenesis of nephrotic syndrome is not fully clear.Most pepole believe that it is associated with the disorder of immune function.As immunoregulatory factors,interleukins(IL) and interferon(IFN) are closely related with the onset of nephrotic syndrome.In this paper,we review the role of IL-21 and INF-γin pathogenesis of nephrotic syndrome.