Advances of polypeptide fragment of rabiesvirus glycoprotein as a brain-targeting carrier / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 607-611, 2017.
Article
Dans Zh
| WPRIM
| ID: wpr-615849
Responsable en Bibliothèque :
WPRO
ABSTRACT
Polypeptide fragment of rabies virus glycoprotein(RVG)has become one of the most popular polypeptides in drug delivery field,because of its advantages of neurotropiam,penetration of blood-brain barrier and biosafety.Polypeptide fragment of RVG can directly deliver proteins and nucleic acids into brain.Additionally,when polypeptide fragment of RVG couples with drug-loading polymers,nanoparticles or liposomes,it can mediate the latters into brain.The application of the RVG polypeptide fragment provides a safe and effective approach for the treatment of brain diseases with biomolecules,such as chemicals,proteins.plasmids,siRNA,miRNA.
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Indice:
WPRIM
langue:
Zh
Texte intégral:
Chinese Pharmacological Bulletin
Année:
2017
Type:
Article