The Effect of Propofol on Pruritus induced by Epidural Morphine / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 423-426, 1997.
Article
Dans Coréen
| WPRIM
| ID: wpr-62022
ABSTRACT
BACKGROUND:
Epidural morphine is used commonly for postoperative pain control. But, pruritus, although trivial, is a common side effect. It is reported that subhypnotic doses of propofol are effective against pruritus induced by epidural or subarachnoid morphine.METHODS:
Sixty five patients received epidural morphine 4 mg bolus and 4 mg/day with continuous infusion for 2 days via Baxter infusor. The patients who have pruritus with scratching were allocated randomly to receive either 1 ml propofol(10 mg) or 1 ml placebo(Intralipos ) intravenously. Pruritus was assessed 5 min later using a pruritus rating scale with double-blind, placebo-controlled study.RESULTS:
Forty patients showed pruritus with scratching. The overall success rate in treating pruritus was 75% in propofol group and 25% in placebo group. Compared with placebo, propofol was effective significantly(P<.05).CONCLUSIONS:
These results suggest that propofol in a subhypnotic dose is an efficient drug treatment for epidural morphine induced pruritus.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Douleur postopératoire
/
Prurit
/
Pompes à perfusion
/
Propofol
/
Analgésiques
/
Anesthésiques
/
Morphine
Type d'étude:
Essai clinique contrôlé
Limites du sujet:
Humains
langue:
Coréen
Texte intégral:
Korean Journal of Anesthesiology
Année:
1997
Type:
Article
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