Synthesis of a new chitosan derivative and assay of Escherichia coli adsorption / 药物分析学报
Journal of Pharmaceutical Analysis
;
(6): 39-45, 2011.
Article
Dans Chinois
| WPRIM
| ID: wpr-621909
ABSTRACT
A new chitosan derivative is prepared using chitosan.Ethyl chlorocarbonate was first introduced to the hydroxyl group of phthaloylchitosan through a nucleophilic reaction.Hydrazine was then added to recover the amino groups of chitosan and promote cross-linking.The structure of this new chitosan derivative was characterized by Fourier transform infrared(FT-IR)and proton nuclear magnetic resonance(1H NMR)spectroscopy,and its physical properties were determined by X-ray diffraction(XRD),differential scanning calorimetry(DSC),and thermogravimetric analysis(TGA).The thermal and chemical stabilities of the new derivative were improved compared with those of native chitosan.Assay of Escherichia coli adhesion on a film based on this chitosan derivative showed good adsorption and biofilm formation.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Journal of Pharmaceutical Analysis
Année:
2011
Type:
Article
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