Thrombocytopenia With Valproate And Clozapine Combination Therapy
ASEAN Journal of Psychiatry
;
: 1-4, 2011.
Article
Dans Anglais
| WPRIM
| ID: wpr-625597
ABSTRACT
Objective:
The occurrence of thrombocytopenia with valproate and clozapine combination therapy has not been noted in the literature. This case report highlights thrombocytopenia as a potential outcome of drug-drug interaction between valproate and clozapine, and serves to remind practitioners that regular monitoring of platelet counts is necessary in such combination therapy.Method:
We report on a patient on valproate therapy who developed thrombocytopenia when clozapine was added to her treatment regime.Results:
Thrombocytopenia resolved 1 week after valproate was tailed off and the patient was placed on clozapine monotherapy.Conclusions:
A precise pathophysiologic understanding of valproate and clozapine-induced thrombocytopenia is lacking, and further studies are required.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Anglais
Texte intégral:
ASEAN Journal of Psychiatry
Année:
2011
Type:
Article
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