The recent trend of prenatal screening
Journal of Genetic Medicine
; : 7-14, 2008.
Article
de Ko
| WPRIM
| ID: wpr-62807
Bibliothèque responsable:
WPRO
ABSTRACT
Twenty years have passed since a prenatal screening for Down syndrome and neural tube defect was applied to obstetric field. The Quad test (AFP, hCG, uE3, Inhibin-A) of the second trimester and the combination test (PAPP-A, hCG, NT) of the first trimester became popular now. The recent trend of prenatal screening is to combine these two screening tests together in order to increase a detection rate of Down syndrome. Three types of screening methods are introduced as follows; integrated test, sequential test and contingent test. In addition to combination of each test, an incorporation of characteristic ultrasound findings of Down syndrome is suggested for its risk calculation. The absence of fetal nasal bone would be a very useful marker especially in the first trimester screening test. According to a change of way calculating risk of Down syndrome, obstetrician's role will be more increased not by passive participation, but by active participation using ultrasound in risk calculation.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Deuxième trimestre de grossesse
/
Premier trimestre de grossesse
/
Diagnostic prénatal
/
Thiazoles
/
Carbamates
/
Adénine
/
Dépistage de masse
/
Syndrome de Down
/
Quinolinone
/
Désoxycytidine
Type d'étude:
Diagnostic_studies
/
Prognostic_studies
/
Screening_studies
Limites du sujet:
Female
/
Humans
/
Pregnancy
langue:
Ko
Texte intégral:
Journal of Genetic Medicine
Année:
2008
Type:
Article