Associations of MRI-lesions and clinical features with disability in Chinese patients with multiple sclerosis
Neurology Asia
; : 391-399, 2013.
Article
de En
| WPRIM
| ID: wpr-628568
Bibliothèque responsable:
WPRO
ABSTRACT
Objective: To analyze associations of MRI-lesions and clinical features with disability in patients with multiple sclerosis (MS) in Shanghai, China. Methods: We studied patients with MS, identified from a survey in Shanghai, whose sites of lesions in the CNS was based on the MRI examinations. Associations between MRI-lesions, various clinical variables and the severity of disability were analyzed with univariate and multivariate logistic regression analysis. Results: There were 210 patients in this study. The disability of the patients with lesions confined to the spinal cord was significantly more severe than those with lesions in the brain (p < 0.008). Current age (OR: 1.041, 95% CI: 1.007~1.077), MS duration (OR: 1.082, 95% CI: 1.011~1.159) and MRI-lesions in the spinal cord (OR: 2.441, 95% CI: 1.039~5.737) were significantly associated with severity of disability on multivariate logistic regression analysis. Conclusion: MRI-lesions in the spinal cord, older age, a longer MS duration were significantly associated with a more severe disability in this MS study in Shanghai China.
Texte intégral:
1
Indice:
WPRIM
Type d'étude:
Prognostic_studies
langue:
En
Texte intégral:
Neurology Asia
Année:
2013
Type:
Article