The role of psychological resilience, severity of disease and treatment adherence in the prediction of health-related quality of life in patients with multiple sclerosis
Neurology Asia
; : 263-268, 2015.
Article
de En
| WPRIM
| ID: wpr-628987
Bibliothèque responsable:
WPRO
ABSTRACT
Objective: This cross-sectional study aims to evaluate the impact of the disability status, psychological resilience, and treatment adherence on health-related quality of life (QOL) in patients with multiple sclerosis (MS). Methods: One hundred MS outpatients, 80 women and 20 men, referred to a clinic of Shiraz University of Medical Sciences, were eligible to participate. MS was diagnosed by 2010 revised Mc-Donald criteria. The QOL and resilience were evaluated by the Medical Outcomes Study Short-Form (SF-36) and Connor-Davidson Resilience Scale (CD-RISC) respectively. Medication adherence and severity of disease were assessed by the Morisky Medication Adherence Scale (MMAS) and expanded disability status state (EDSS) scores respectively. Results: Stepwise multiple regressions showed that in the first model, the disability status was the best predictor which accounted for 28.1% of the variance in QOL. In the second model, both the disability status and resilience explained 50.6% of the variation in QOL. Conclusion: The findings showed that the severity of the disease is a strong predictor which has adverse effects on the physical component of health-related QOL in the patients with MS. Both psychological resilience and treatment adherence have positive influence on mental component of QOL in these patients.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Qualité de vie
/
Sclérose en plaques
Type d'étude:
Observational_studies
/
Prognostic_studies
langue:
En
Texte intégral:
Neurology Asia
Année:
2015
Type:
Article