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In vitro development of autologous tissue engineered human articular neocartilage for orthopaedic surgery
The Medical Journal of Malaysia ; : 15-16, 2004.
Article Dans Malayalam | WPRIM | ID: wpr-629917
ABSTRACT
Treatment of articular cartilage lesions remains a clinical challenge. The uses of prosthetic joint replace allograft and/or autograft transplant carry a risk of complications due to infection, loosening of its component, immunological rejection and morbidity at the donor site. There has been an increasing interest in the management of cartilage damages, owing to the introduction of new therapeutic options. Tissue engineering as a method for tissue restoration begins to provide a potential alternative therapy for autologous grafts transplantations. We aimed to evaluate how well a tissue engineered neocartilage implant, consist of human articular chondrocytes cultured with the presence of autologous serum and mixed in a fresh fibrin derived from patient, would perform in subcutaneous implantation in athymic mice.
Sujets)
Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Phénomènes biomécaniques / Cartilage articulaire / Chondrocytes / Procédures orthopédiques / Milieux de culture / Ingénierie tissulaire / Sérum / Souris nude langue: Malayalam Texte intégral: The Medical Journal of Malaysia Année: 2004 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Phénomènes biomécaniques / Cartilage articulaire / Chondrocytes / Procédures orthopédiques / Milieux de culture / Ingénierie tissulaire / Sérum / Souris nude langue: Malayalam Texte intégral: The Medical Journal of Malaysia Année: 2004 Type: Article