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Apoptosis changes and SA-beta galactosidase expression in stress-induced premature senescence (SIPS) model of human skin fibroblasts
The Medical Journal of Malaysia ; : 71-72, 2008.
Article Dans Malayalam | WPRIM | ID: wpr-629983
ABSTRACT
Stress-induced premature senescence (SIPS) model is in vitro model of cellular aging. In this study, apoptosis was evaluated in SIPS model and in replicative senescent fibroblasts. We also compared the activity of senescence-associated beta-galactosidase (SA-beta gal) as a biomarker of cellular aging. Our results suggested that SIPS model and senescent fibroblasts might share similar mechanism of aging and apoptosis pathway.
Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) langue: Malayalam Texte intégral: The Medical Journal of Malaysia Année: 2008 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) langue: Malayalam Texte intégral: The Medical Journal of Malaysia Année: 2008 Type: Article