Determination of the diagnostic accuracy of saline infusion sonography in the evaluation of postmenopausal bleeding: a preliminary study

ABSTRACT

Objective: To determine the diagnostic accuracy of transvaginal ultrasound and saline infusion sonography in the evaluation of postmenopausal bleeding. Setting: Philippine General Hospital Design: Cross-sectional study. Transvaginal sonography and saline infusion sonography were performed and findings correlated with histopathologic results obtained by hysteroscopy or endometrial biopsy. Results: At a 95 percent confidence interval, the sensitivity of TVS was higher than SIS (92.9 percent), the specificity of SIS was greater than TVS (50 percent vs 0). The positive predictive value and negative predictive of SIS (91.7 percent, 50 percent) were both greater than that obtained by TVS (86.7 percent, 0). Comparing these two proportions, there was no sufficient evidence to say that there exists a significant difference. Conclusion: Transvaginal sonography and saline infusion sonography are invaluable tools in the evaluation of postmenopausal bleeding.