Concise Review: Differentiation of Human Adult Stem Cells Into Hepatocyte-like Cells In vitro
International Journal of Stem Cells
;
: 49-54, 2014.
Article
Dans Anglais
| WPRIM
| ID: wpr-63302
ABSTRACT
Adult stem cells (ASCs) are undifferentiated cells found throughout the body that divide to replenish dying cells and regenerate damaged tissues, which are the powerful sources for cell therapy and tissue engineering. Bone marrow-derived mesenchymal stem cells (BMSCs), adipose tissue-derived mesenchymal stem cells (ADSCs), and peripheral blood monocytes (PBMCs) are the common ASCs, and many studies indicated that ASCs isolated from various adult tissues could be induced to hepatocyte-like cells in vitro. However, the isolation, culture protocols, characterization of ASCs and hepatocyte-like cells are different. This review aims to describe the isolation and culture procedures for ASCs, to summarize the molecular characterization of ASCs, to characterize function of hepatocyte-like cells, and to discuss the future role of ASCs in cell therapy and tissue engineering.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Monocytes
/
Ingénierie tissulaire
/
Cellules souches adultes
/
Cellules souches mésenchymateuses
/
Thérapie cellulaire et tissulaire
Type d'étude:
Guide de pratique
Limites du sujet:
Adulte
/
Humains
langue:
Anglais
Texte intégral:
International Journal of Stem Cells
Année:
2014
Type:
Article
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