Comparative study on the use of conjunctival autograft with or without mitomycin-C in pterygium surgery
Philippine Journal of Ophthalmology
;
: 73-77, 2014.
Article
Dans Anglais
| WPRIM
| ID: wpr-633488
ABSTRACT
@#<p style="text-align justify;"><strong>OBJECTIVE:
</strong> To compare the recurrence rate after conjunctival autograft alone versus conjunctival autograft with mitomycin-C in the treatment of primary and recurrent pterygium.<br /><strong>METHODS:
</strong> This was a prospective, randomized, interventional comparative study of patients with primary and recurrent pterygium who were randomized to receive either simple excision with conjunctival autograft (CA) or simple excision with CA and mitomycM-C applied. They were followed up for 6 months and observed for recurrence of the pterygium. Statistical analyses were used to compare the 2 groups.<br /><strong>RESULTS:
</strong> Fifty-eight patients (62 eyes) diagnosed with primary and recurrent pterygium were evaluated. The mean age was 44.81 ± 12.35 years (range 25 to 70 years). Thirty eyes were treated with conjunctival autograft (15 primary, 15 recurrent) and 32 eyes (17 primary, 15 recurrent) with conjunctival autograft combined with Mtraoperati-ve application of low-dose raitomycin. -C (0.02% for 3 minutes). The mean follow-up period was 25 ± 1.40 months (range 24 to 28 months). There was a 3.22% recurrence rate (2 eyes) from the recurrent pterygium group. There was no significant difference 11.1 the rate of recurrence (p = 0.53) between the 2 treatments for both primary and recurrent pterygium. No mitomycM C-related complication was observed during the length of the study.<br /><strong>CONCLUSION:
</strong> Conjunctival autograft surgery alone for primary and recurrent pterygium is effective and safe in reducing the recurrence rate of pterygium within" 6 months.</p>
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Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Transplantation autologue
/
Ptérygion
/
Mitomycine
/
Conjonctive
/
Autogreffes
Type d'étude:
Essai clinique contrôlé
Limites du sujet:
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Philippine Journal of Ophthalmology
Année:
2014
Type:
Article
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