Bilateral primary pigmented nodular adrenocortical disease: a case of report describing a rare cause of Cushing's syndrome
Journal of Korean Medical Science
;
: 450-457, 1994.
Article
Dans Anglais
| WPRIM
| ID: wpr-63371
ABSTRACT
A case of Cushing's syndrome due to bilateral pigmented nodular adrenal disease in a 35-year-old male is presented. The adrenals showed multiple, black, variable sized nodules. Histologically the cells contained lipofuscin and either had a clear cytoplasm or an eosinophilic cytoplasm with a prominent nucleus. Lymphocytic infiltration and fatty metaplasia within the nodules are two of the prominent histological features. There is extreme internodular atrophy which suggests that primary pigmented nodular adrenocortical disease is a non-adrenocorticotropic hormone dependent condition. Since the disorder appears to involve primarily the cortex of both adrenals, the treatment of choice is bilateral adrenalectomy followed by steroid replacement. The characteristic clinicopathological manifestations that separate this diagnosis from other types of adrenal disease are also discussed. This is the first reported case in Korea to be documented with the pertinent clinicopathological findings.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Atrophie
/
Dexaméthasone
/
Hydrocortisone
/
Organites
/
Tissu adipeux
/
Cortex surrénal
/
Surrénalectomie
/
Syndrome de Cushing
/
Furosémide
/
Inflammation
Limites du sujet:
Adulte
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Journal of Korean Medical Science
Année:
1994
Type:
Article
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