Application effect of recombinant human epidermal growth factor derivative Eye drops in treatment of dry eye / 国际眼科杂志(Guoji Yanke Zazhi)

ABSTRACT

Abstract? AlM To investigate the application effect of recombinant human epidermal growth factor derivative eye drops ( Jinyinshu) in treatment of dry eye.?METHODS:Sixty cases ( 87 eyes ) of dry eye patients were randomly divided into control group and observation group, 42 eyes and 45 eyes respectively. The control group received Chondroitin sulfate eye drops treatment, and the observation group were used for treatment of Jinyinshu. The changes of clinical efficacy, correlation index (symptom score, BUT, S l t, FL) before and after treatment, quality of life after treatment and the incidence of adverse reactions were compared.? RESULTS: ln the control group, the total clinical effective rate was 71%, which was significantly lower than that in the observation group ( 91%) , the difference was statistically significant ( P0. 05).?CONCLUSlONJinyinshu is significantly effective in the treatment of dry eye, and its clinical efficacy is better than chondroitin sulfate.