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New research progress of microRNAs in retinoblastoma / 国际眼科杂志(Guoji Yanke Zazhi)
International Eye Science ; (12): 1995-1998, 2014.
Article Dans Chinois | WPRIM | ID: wpr-637079
ABSTRACT
Retinoblastoma(RB)is the most common intraocular malignancy of children with extremely poor prognosis. MicroRNAs are small non-coding single-stranded RNAs in eukaryotic cells, which regulate the expression of gene by mRNA degradation or translation inhibition. MicroRNAs, acting as oncogenes or tumor suppressor genes, are associated with the occurrence and development of RB directly, which is vital for the early diagnosis and clinical targeted therapy of RB. This review summarized the expression of microRNAs in RB and the related mechanism.

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Type d'étude: Étude de dépistage langue: Chinois Texte intégral: International Eye Science Année: 2014 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Type d'étude: Étude de dépistage langue: Chinois Texte intégral: International Eye Science Année: 2014 Type: Article