Experimental study progress in retinal disease immunomodulation by mesenchymal stem cells / 中华实验眼科杂志

ABSTRACT

Mesenchymal stem cells (MSCs) derive mainly from the mesoderm pluripotent stem cells,with wide variety of sources,easily accessible,low immunogenicity,pluripotent,various damage repair,nutrition,and other features and functions.MSCs are widely used for clinical treatment of various diseases.In recent years,scholars deepens various physiological characteristics of MSCs,and the MSCs have been used in the treatment of retinal diseases.In this paper,the characteristics of the MSCs,such as immune markers,immunomodulatory properties,the role of nutrition and MSCs immune on diabetic retinopathy (DR),retinal degenerative diseases,choroidal neovascular (CNV),retinal ischemia-reperfusion immunomodulatory applications were reviewed.