Postoperative tear dysfunction of LASIK and SMILE / 中华实验眼科杂志

ABSTRACT

Tear dysfunction was considered as abnormalities of tear film composition that include the presence of pro-inflammatory cytokines.Recent studies indicated that altered tear composition caused dysfunction,accelerated death and detachment of the superficial epithelium,leading to an irregular corneal surface,an unstable tear layer and hyperesthesia of the corneal nerve endings.Symptoms of tear dysfunction after laser in situ keratomileusis (LASIK) and small incision lenticule extraction (SMILE) present in many patients.This review summarized the clinical characteristics of tear dysfunction in post-LASIK and post-SMILE patients,analyzed the potential mechanism of tear dysfunction and reasonable management.