Effects of interleukin-1? on discharge of neurons in paraventricular nuclei of rat hypothalamus / 上海第二医科大学学报
Article
de Zh
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| ID: wpr-640817
Bibliothèque responsable:
WPRO
ABSTRACT
Objective To observe the effects of interleukin-1 ?(IL-1?) on spontaneous electrical activity of neurons in paravenrticular nuclei,and discuss the possible mechanism.MethodsExtracellular recording technique was employed to observe the effects of IL-1? on spontaneous electrical activity of neurons in paravenricular nuclei in rat hypothalamic slices,and the influence of losartan on the electrical activity induced by IL-1? was examined.ResultsAfter exposure to IL-1?(1?10-7 mol/L),the discharge frequency was significantly increased in 46 of the 59 discharge units(78%) of neurons(P
Texte intégral:
1
Indice:
WPRIM
langue:
Zh
Texte intégral:
Journal of Shanghai Jiaotong University(Medical Science)
Année:
2006
Type:
Article