Acute Lymphoblastic Leukemia Manifesting as Acute Vogt-Koyanagi-Harada Disease
Korean Journal of Ophthalmology
;
: 325-328, 2009.
Article
Dans Anglais
| WPRIM
| ID: wpr-64096
ABSTRACT
We describe a case of bilateral exudative retinal detachment associated with prodromal symptoms simulating the presentation of acute Vogt-Koyanagi-Harada disease that was eventually diagnosed as acute lymphoblastic leukemia. A 42-year-old man presented with sudden visual loss in both eyes for two weeks. He complained of intermittent headache, neck stiffness and tinnitus for a month. His best-corrected visual acuities were 20/200 in both eyes. Fluorescein angiography, optical coherence topography and indocyanine green angiography featured bilateral serous retinal detachments. A clinical diagnosis of incomplete type Vogt-Koyanagi-Harada disease was considered. However, complete blood cell count showed a marked increase in the number of white blood cells and bone marrow examination revealed precursor B cell lymphoblastic leukemia. The patient started on induction chemotherapy. A week later, his best-corrected visual acuities were 20/25 and the serous retinal detachments were nearly absorbed in both eyes. Bilateral exudative retinal detachment associated with neurologic and auditory abnormalities may be a presenting sign of acute lymphoblastic leukemia. Clinicians should be aware of the possibility of leukemia in such patients.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Décollement de la rétine
/
Angiographie fluorescéinique
/
Acuité visuelle
/
Syndrome uvéo-méningo-encéphalique
/
Études de suivi
/
Tomographie par cohérence optique
/
Diagnostic différentiel
/
Leucémie-lymphome lymphoblastique à précurseurs B et T
/
Fond de l'oeil
Type d'étude:
Etude diagnostique
/
Étude observationnelle
/
Étude pronostique
Limites du sujet:
Adulte
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Korean Journal of Ophthalmology
Année:
2009
Type:
Article
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