The labeling and animal study of tumor positive imaging agent 5-18F-fluorouracil / 中华核医学杂志
Chinese Journal of Nuclear Medicine
;
(6): 121-122, 2001.
Article
Dans Chinois
| WPRIM
| ID: wpr-642679
ABSTRACT
Objective To synthesize and label a tumor positive imaging agent 18F-fluorouracil (FU) and the animal study on the product was also undertaken. Methods 18F-FU was synthesized and labeled. Its biodistribution analysis was done on normal and tumor bearing nude mice. PET imaging was performed on normal and tumor bearing rabbits. Results HPLC analysis and other quality control test results guaranteed the possibility of animal study and clinical usage of 18F-FU. Biodistribution analysis and PET imaging also demonstrated a high accumulation of the tracer in tumor tissue. Conclusion 18F-FU is a kind of potential tumor positive imaging agents which can be used to assess the effects of chemotherapy.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Journal of Nuclear Medicine
Année:
2001
Type:
Article
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