Optimal Continuous Positive Airway Pressure Level in Korean Patients with Obstructive Sleep Apnea Syndrome
Clinical and Experimental Otorhinolaryngology
;
: 207-211, 2010.
Article
Dans Anglais
| WPRIM
| ID: wpr-64535
ABSTRACT
OBJECTIVES:
The aim of this study was to investigate optimal continuous positive airway pressure (CPAP) level, to examine the factors affecting optimal CPAP level, and to develop a predictive equation for optimal CPAP level in Korean patients with obstructive sleep apnea syndrome (OSAS).METHODS:
A total of 202 patients with OSAS who underwent successful manual titration for CPAP treatment were included in this study. Correlations between the optimal CPAP level and baseline data including anthropometric and polysomnographic variables were analyzed. A predictive equation for optimal CPAP level was developed based on anthropometric and polysomonographic data.RESULTS:
The mean optimal CPAP level in 202 patients with OSAS was 7.8+/-2.3 cm H2O. The mean optimal CPAP level in the mild, moderate, and severe OSAS groups was 6.0+/-1.3, 7.4+/-1.9, and 9.1+/-2.1 cm H2O, respectively. The apneahypopnea index (AHI) (r=0.595, P<0.001), arousal index (r=0.542, P<0.001), minimal SaO2 (r=-0.502, P<0.001), body mass index (BMI) (r=0.494, P<0.001), neck circumference (r=0.265, P<0.001), and age (r=-0.164, P=0.019) were significantly correlated with optimal CPAP level. The best predictive equation according to stepwise multiple linear regression analysis was Optimal CPAP level (cm H2O)=0.681+(0.205xBMI)+(0.040xAHI). Forty-two percent of the variance in the optimal CPAP level was explained by this equation (R2=0.42, P<0.001).CONCLUSION:
A predictive equation for optimal CPAP level in Korean patients with OSAS was developed using AHI and BMI, which can be easily measured during the diagnostic process.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Éveil
/
Indice de masse corporelle
/
Modèles linéaires
/
Polysomnographie
/
Syndrome d'apnées obstructives du sommeil
/
Ventilation en pression positive continue
/
Cou
Type d'étude:
Guide de pratique
/
Étude pronostique
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Clinical and Experimental Otorhinolaryngology
Année:
2010
Type:
Article
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