Your browser doesn't support javascript.
loading
Histological and Morphological Change of Implanted Reinforcement Gore-Tex(R) in Nasal Dorsum of Rabbit / 대한이비인후과학회지
Korean Journal of Otolaryngology - Head and Neck Surgery ; : 705-711, 2008.
Article Dans Coréen | WPRIM | ID: wpr-645371
ABSTRACT
BACKGROUND AND

OBJECTIVES:

For nasal augmentation surgery, several materials have been used. Porous material, expanded polytetrafluoroethylene (Gore-Tex(R)) contains numerous pores which allow stability of the implant, but this advantage has been tempered by unpredictable outcomes. The purpose of this study is to evaluate morphological and histological changes of reinforced Gore-Tex(R) in the rabbit model. MATERIALS AND

METHOD:

Twenty New Zealand white rabbits were used. The reinforced Gore-Tex(R) block was implanted in the nasal dorsum. According to the duration of implantation, rabbits were divided into four groups such as 1, 3, 6 and 12 months. The animals were grossly examined with respect to the status of the Gore-Tex(R). We evaluated the three-dimensional size of the implants over time and used light and electron microscopy to investigate the histological changes associated with the whole tissue blocks.

RESULTS:

Grossly, none of the implants was lost or extruded and there was no evidence of wound infection. Diminution rates of thickness, width and height in the implants were respectively 16.7%, 7.5%, and 3.5%. Histologically, the growth of connective tissue was observed in all specimens and internodal space was decreased by connective tissue ingrowth as time goes on. Neovascularization was observed in the groups for which duration was longer than 6 months, and degenerative changes were also observed in the groups over 6 month of implanted duration.

CONCLUSION:

The reinforced e-PTFE should be carefully trimmed because of the possibility of decreasing size over time. And additional studies are needed to further investigate the stability of Gore-Tex(R).
Sujets)

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Polytétrafluoroéthylène / / Rhinoplastie / Infection de plaie / Microscopie électronique / Tissu conjonctif / Imidazoles / Lumière / Composés nitrés Limites du sujet: Animaux langue: Coréen Texte intégral: Korean Journal of Otolaryngology - Head and Neck Surgery Année: 2008 Type: Article

Documents relatifs à ce sujet

MEDLINE

...
LILACS

LIS

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Polytétrafluoroéthylène / / Rhinoplastie / Infection de plaie / Microscopie électronique / Tissu conjonctif / Imidazoles / Lumière / Composés nitrés Limites du sujet: Animaux langue: Coréen Texte intégral: Korean Journal of Otolaryngology - Head and Neck Surgery Année: 2008 Type: Article