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Salvage Surgery for Radiation Failures in Early(T1N0, T2N0) Glottic Cancer / 대한이비인후과학회지
Korean Journal of Otolaryngology - Head and Neck Surgery ; : 795-799, 2007.
Article Dans Coréen | WPRIM | ID: wpr-645578
ABSTRACT
BACKGROUND AND

OBJECTIVES:

This study was undertaken to analyze the complications, recurrences, functional results and survival in patients undergoing salvage surgery for recurrent glottic cancers after previous radiotherapy. SUBJECTS AND

METHOD:

Records of twenty-seven patients were retrospectively reviewed. There were 26 men and 1 woman with the median age of 63 years. The stage at initial treatment was T1a in 16 patients, T1b in 5 patients and T2 in 6 patients. Fifteen patients underwent total laryngectomy, and 12 patients had partial laryngectomy. Neck dissection was combined for 2 patients who had recurred neck metastasis and for 3 patients electively. All patients have been followed up for at least 1 year or until their death (6-159 months, median 31 months).

RESULTS:

Overall voice preservation was achieved in 29.6% of the patients. The 5-year overall survival and disease-specific survival rates were 75.0% and 81.2%, respectively. Early and late complications, duration of hospital stay, local recurrences, neck recurrences and disease-specific survival were not significantly different between partial and total laryngectomy. Duration of tube feeding was shorter in partial laryngectomy (p=0.016). Neck recurrence was the most common cause of death, and it occurred in patients with recurred tumor that was locally advanced or re-recurrent after salvage surgery.

CONCLUSION:

In selected cases, recurrences after failure to radiotherapy in T1-T2 glottic cancer could be salvaged with partial laryngectomy with adequate tumor control and acceptable morbidity. Elective neck dissection is recommended in locally advanced recurrent or re-recurrent glottic cancer.
Sujets)

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Évidement ganglionnaire cervical / Radiothérapie / Récidive / Voix / Tumeurs du larynx / Taux de survie / Études rétrospectives / Cause de décès / Nutrition entérale / Glotte Type d'étude: Étude observationnelle Limites du sujet: Femelle / Humains / Mâle langue: Coréen Texte intégral: Korean Journal of Otolaryngology - Head and Neck Surgery Année: 2007 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Évidement ganglionnaire cervical / Radiothérapie / Récidive / Voix / Tumeurs du larynx / Taux de survie / Études rétrospectives / Cause de décès / Nutrition entérale / Glotte Type d'étude: Étude observationnelle Limites du sujet: Femelle / Humains / Mâle langue: Coréen Texte intégral: Korean Journal of Otolaryngology - Head and Neck Surgery Année: 2007 Type: Article