A Case of Adenomatoid Hamartoma Originated from Nasal Cavity / 대한이비인후과학회지

ABSTRACT

Hamartomas are non-neoplastic malformations or congenital errors of tissue development. They are characterized by an abnormal mixture of tissues indigenous to that area of the body, but with an excess of one or more of the tissue types. Adenomatoid hamartomas are pathologically unique-appearing sinonasal tract and nasopharyngeal lesions and defined as follows ; the glandular component of the hamartoma consisted of respiratory epithelium originating from the surface epithelium, and polypoid growth resulted from respiratory epithelial-lined adenomatoid proliferation. Hamartomas occur in all areas of the body, especially in the liver, spleen, kidney and lung, but very rarely in the nasal cavity, paranasal sinuses, or nasopharynx. The histopathological differential diagnosis of adenomatoid hamartoma of the sinonasal tract includes inverted papilloma and adenocarcinoma. Misinterpretation as a true neoplasm may result in unnecessary radical surgery. We present a case of adenomatoid hamartoma in the nasal cavity, which was treated with complete resection by endonasal endoscopic approach.