Seroprevalence of Brucellosis in Human Immunodeficiency Virus Infected Patients in Hamadan, Iran
Osong Public Health and Research Perspectives
; (6): 282-288, 2017.
Article
de En
| WPRIM
| ID: wpr-649039
Bibliothèque responsable:
WPRO
ABSTRACT
OBJECTIVES: Brucellosis is a systemic disease with a wide spectrum of clinical manifestations. This study aimed to determine the seroprevalence of brucellosis in human immunodeficiency virus (HIV) infected patients in Hamadan Province in the west of Iran. METHODS: A total of 157 HIV-infected patients were screened through standard serological tests, including Wright’s test, Coombs’ Wright test, and 2-mercaptoethanol Brucella agglutination test (2ME test), blood cultures in Castaneda media, and CD4 counting. Data were analyzed using Stata version 11. RESULTS: Wright and Coombs’ Wright tests were carried out, and only 5 (3.2%) patients had positive serological results. However, all patients had negative 2ME results, and blood cultures were negative for Brucella spp. Moreover, patients with positive serology and a mean CD4 count of 355.8 ± 203.11 cells/μL had no clinical manifestations of brucellosis, and, and the other patients had a mean CD4 count of 335.55 ± 261.71 cells/μL. CONCLUSION: Results of this study showed that HIV infection is not a predisposing factor of acquiring brucellosis.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Brucella
/
Brucellose
/
Tests d'agglutination
/
Tests sérologiques
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Infections à VIH
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Études séroépidémiologiques
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Causalité
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VIH (Virus de l'Immunodéficience Humaine)
/
Numération des lymphocytes CD4
/
Iran
Type d'étude:
Diagnostic_studies
Limites du sujet:
Humans
Pays comme sujet:
Asia
langue:
En
Texte intégral:
Osong Public Health and Research Perspectives
Année:
2017
Type:
Article