Re-evaluation of Association between Thrombotic Diasthesis and Legg-Calve-Perthes Disease / 대한정형외과학회잡지
The Journal of the Korean Orthopaedic Association
;
: 189-194, 1999.
Article
Dans Coréen
| WPRIM
| ID: wpr-650650
ABSTRACT
Legg-Calve-Perthes disease (LCP) has been reported to be associated with hypofibrinolysis and a deficiency in coagulation. The goal of this prospective study was to confirm or refute these findings and to establish a guide for a screening test. The coagulation systems of twenty-three patients with Legg-Calve-Perthes disease were evaluated by means of the tests which included prothrombin time, activated partial thromboplastin time, antithrombin-III (AT-III), protein C, protein S, lipoprotein(a), and anticardiolipin antibody (ACA). Study subjects were 21 males and 2 females. Mean age was 8.7 years. No abnormal results were found for Antithrombin-III and Protein S, but 2 patients had low Protein C level. Two of 23 patients had Lipoprotein(a) values greater than 30 mg/dl. Another two patients had positive finding for Anticardiolipin antibody. There were no statistical differences in all parameters between Catterall group stage in the patients with Legg-Calve-Perthes disease. We were unable to establish an association between thrombotic tendency and Legg-Calve-Perthes disease based on this prospective study. So, routine screening of patients with Legg-Calve-Perthes disease for abnormalities of antithrombotic factors would be not warranted.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Temps partiel de thromboplastine
/
Temps de prothrombine
/
Protéine C
/
Dépistage de masse
/
Études prospectives
/
Protéine S
/
Lipoprotéine (a)
/
Anticorps anticardiolipines
/
Maladie de Legg-Calve-Perthes
Type d'étude:
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
/
Étude de dépistage
Limites du sujet:
Femelle
/
Humains
/
Mâle
langue:
Coréen
Texte intégral:
The Journal of the Korean Orthopaedic Association
Année:
1999
Type:
Article
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