Peripheral Primitive Neuroectodermal Tumor with Osseous Component of the Small Bowel Mesentery: A Case Study
Korean Journal of Pathology
;
: 77-81, 2013.
Article
Dans Anglais
| WPRIM
| ID: wpr-65405
ABSTRACT
A case of peripheral primitive neuroectodermal tumor of the small bowel mesentery with osseous component is reported. A 23-year-old man was admitted to our hospital because of acute severe abdominal pain. Abdominal computed tomography revealed a large solid and cystic, oval shaped mass, measuring 11.0x6.0 cm in the pelvic cavity. Histologically the resected lesion consisted of sheets of undifferentiated small round cells forming Homer-Wright rosettes and perivascular pseudorosettes, and showed areas of osteoid and bone formation. Immunohistochemical studies revealed that tumor cells expressed positivity against CD99 (MIC2), CD57, neuron-specific enolase, and vimentin. Fluorescence in situ hybridization study revealed Ewing sarcoma breakpoint region 1 (EWSR1) gene rearrangement on chromosome 22q12. To the authors' knowledge this is the first documentation of a peripheral neuroectodermal tumor with osteoid and bone formation of the small bowel mesentery.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Ostéogenèse
/
Enolase
/
Sarcome d'Ewing
/
Vimentine
/
Réarrangement des gènes
/
Douleur abdominale
/
Hybridation in situ
/
Tumeurs neuroectodermiques primitives
/
Tumeurs neuroectodermiques primitives périphériques
/
Fluorescence
langue:
Anglais
Texte intégral:
Korean Journal of Pathology
Année:
2013
Type:
Article
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