Efficacy of ultrasound-guided nerve block anesthesia combined with Danshen injection on the treatment of angina and its influence on serum indexes / 中国生化药物杂志

ABSTRACT

Objective To investigate the efficacy of ultrasound-guided nerve block anesthesia combined with Danshen injection on the treatment of angina and its influence on serum indexes. Methods 178 patients with angina in Huzhou central hospital from July 2015 to February 2017 were randomLy divided into the control group (n=89) and the research group (n=89). The control group was given routine western medicine combined with Danshen injection, while the research group was treated with ultrasound-guided nerve block anesthesia combined with Danshen injection. The clinical efficacy, homocysteine (Hcy), adiponectin (APN), tumor necrosis factor-α (TNF-α), high-sensitivity C-reactive protein (hs-CRP), ejection fraction (EF) before and after treatment, adverse reactions were compared between the two groups. Results The total effective rate in the control group (80.90%) was lower than that in the control group (95.51%) (P<0.05); After treatment, the levels of Hcy, TNF-α, hs-CRP in the two groups increased, and the variety range in the research group was larger (P<0.05); The incidence of adverse reactions in the control group and the research group (3.37% VS 1.12%) were compared, there was no statistical difference. Conclusion Ultrasound-guided nerve block anesthesia combined with Danshen injection could effectively improve serum indexes of patients, it has definite efficacy and less adverse reactions, which is worthy of further clinical application and promotion.