Clinical Observation of Modified Yupingfeng Powder Decoction in the Treatment of Elderly Patients with Type 2 Diabetes Hyperhidrosis / 中国药房

ABSTRACT

OBJECTIVE:To observe clinical efficacy and safety of Modified yupingfeng powder decoction in the treatment of elderly patients with type 2 diabetes hyperhidrosis.METHODS:A total of 120 elderly patients with type 2 diabetes hyperhidrosis se-lected from outpatient of our hospital during Jan. 2015 to Jun. 2016 were divided into control group and observation group accord-ing to random number table,with 60 cases in each group. Control group was given routine chemical drug therapy of diabetes. Ob-servation group was additionally given Modified yupingfeng powder,decocted with water,300 mL each time,150 mL morning and night,1 h before meal,on the basis of control group.Treatment courses of 2 groups both were 1 month. Blood glucose index-es(FPG,2 hPG,HbA1c)and TCM symptom scores before and after treatment were compared between 2 groups. Clinical effica-cies and the occurrence of ADR were observed. RESULTS:Before treatment,there was no statistical significance in FPG,2 hPG, HbA1c or TCM symptom scores between 2 groups(P>0.05). Compared to before treatment,FPG,2 hPG,HbA1c and TCM symp-tom scores of 2 groups were decreased significantly after treatment;the levels of FPG,HbA1c and TCM symptom score in observa-tion group were significantly lower than control group,with statistical significance(P<0.05). But there was no statistical signifi-cance in 2 hPG between 2 groups(P>0.05). Total response rate of observation group(90.00%)was significantly higher than that of control group(70.00%),with statistical significance(P<0.05). No obvious ADR was found in 2 groups. CONCLUSIONS:Modified yupingfeng powder decoction can effectively improve the clinical symptoms,and shows good therapeutic efficacy and safety for elderly patients with type 2 diabetes hyperhidrosis.