Prescription optimization and stability investigation of urea ointment / 军事医学
Military Medical Sciences
;
(12): 615-617, 2017.
Article
Dans Chinois
| WPRIM
| ID: wpr-658664
ABSTRACT
Objective To adjust the prescription of urea ointment and investigate its stability .Methods In accordance with the original prescription , four groups of urea ointment were prepared .Group A and group B were made with yellow vaseline from different manufacturers , while groups C and D were prepared in summer and winter respectively with the same source materials.The viscosity and moldability of the four groups were evaluated through the senses .The prescription was slightly adjusted through the single-factor effect experiment .Three batches of urea ointment were prepared according to the new prescription and their stability was investigated .Results Using the original prescription , the urea ointment made with yellow vaseline provided by Manufacturer One had better viscosity and moldability than that from Manufacturer Two .The urea ointment made in summer had lower viscosity and poorer moldability than the one made in winter .The amount of beeswax increased in the adjusted prescription .Three batches of urea ointment were prepared with the new prescription and their stability was maintained .There were no changes in appearance , and the content and microbial limit remained in the standard range for 11 months.Conclusion The source of materials and change of the external environment could affect the characteristics of urea ointment .The adjusted prescription is feasible and stable .
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Military Medical Sciences
Année:
2017
Type:
Article
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