Advances in surgical treatment of Parkinson′s disease / 中国综合临床

ABSTRACT

Parkinson′s disease(PD)is a neurodegenerative disease,there is no effective means of curative treatment.The purpose of treatment is to control the clinical symptoms of patients and delay the development of the disease.The clinical treatment is based on levodopa-based drug treatment as a gold standard, but long-term drug treatment will reduce the efficacy of treatment,and movement fluctuations,dysmotility and other complications would occur at the same time.In recent years,brain deep electrical stimulation,stem cell transplantation,gene therapy and other surgical treatment have been gradually applied in the clinical practice,the technology become more and more mature.In this paper,based on the recent literature,the study of PD surgical treatment of the status quo and progress were reviewed.