Mechanisms of Action of Probiotics / 소아과
Korean Journal of Pediatrics
;
: 691-695, 2005.
Article
Dans Coréen
| WPRIM
| ID: wpr-66428
ABSTRACT
There is scientific evidence that administration of probiotics is effective in the treatment of acute infectious diarrhea in children and the prevention of antibiotic associated diarrhea and nosocomial/ community acquired diarrhea. Probiotics prevent relapse of recurrent pouchitis and decrease the initial onset of pouchitis in ulcerative colitis. Probiotic organisms suppress growth of pathogens as well as their epithelial attachment and/or invasion either directly by secreting antimicrobial substances or by stimulating host expression of protective molecules. Additionally, probiotics enhance mucosal barrier function and can stimulate host production of immunosuppressive molecules that downregulate inflammatory responses or allergic immune response. Mechanisms of action explain therapeutic effects and randomized controlled trials are warranted before recommendations for therapeutic or preventive use can be given.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Récidive
/
Rectocolite hémorragique
/
Pochite
/
Probiotiques
/
Diarrhée
/
Attache épithéliale
Type d'étude:
Essai clinique contrôlé
/
Guide de pratique
Limites du sujet:
Enfant
/
Humains
langue:
Coréen
Texte intégral:
Korean Journal of Pediatrics
Année:
2005
Type:
Article
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