Relationship between Anxiety and Cognitive Function or Activity of Daily Living in Parkinson's Disease Patients / 医学研究杂志

ABSTRACT

Objective To explore the effects of anxiety on cognitive function and activity of daily living in Parkinson's disease patients (PD).Methods Anxiety,cognitive function and activity of daily living in 55 cases of PD patients and 30 cases of normal control group were evaluated by beck anxiety inventory(BAI),montreal cognitive assessment(MOCA) and Barthel index scale (BI).The relationship between BAI score and MoCA score or BI score were analyzed.Results The incidence of PD combined anxiety disorder was as high as 41.8％.MoCA score of anxiety group was significantly lower than the control group and significantly negatively related to the BAI scores(P ＜ 0.05),but there was no statistical difference compared with the anxiety group(P ＞ 0.05).Visual space and executive function,memory and delayed memory score and BI score of the anxiety group were significantly lower than the anxiety group and control group (P ＜ 0.05) and significantly negatively related to the BAI scores (P ＜ 0.05).Visual space and executive function of the non-anxiety group were significantly lower than the control group,but had no significant correlation with the BAI score (P ＞ 0.05).Conclusion PD patients often have a certain degree of cognitive impairment and obvious barriers to daily living activities.Anxiety often has different extent effect on cognitive function in PD patients,especially in the visual space and executive function,memory function,and seriously affects the patient's activity of daily living,makes the life quality decreased obviously.