Comparison of human papilloma virus genotype distribution in cervical lesions / 医学研究生学报

ABSTRACT

Objective The article aimed to study the genotype distribution of human papilloma virus (HPV) in cervical lesions.Methods A retrospective analysis was done in 798 cases of patients with HPV infection in cervical lesions in the Affiliated Hospital of Jiangsu University from January 2015 to December 2015.The patients underwent cervical histological examination and their cervical brush samples were collected within 6 months before the operation for HPV genotyping results in order to explore the relationship between HPV genotypes and cervical lesions.Results Of all the 798 patients undergoing cervical histological examination,there were 759 cases of HPV infection and the total positive rate was 95.11％.Among them,238 cases were mixed infection and the rate of mixed infection was 29.82％.The five most prevalent HPV subtypes of single infection were 16,52,58,53,51.Cervical lesions of different degrees were mainly single infection,while multiple infections were mostly double infections,especially in cervical cancer patients.Conclusion Different HPV subtypes result in different levels of cervical lesions.HPV typing test and cervical biopsy in patients with high-risk HPV infection will be helpful in early detection of cervical lesions.