Role of Hedgehog signaling pathway in the development of retinal cells and pathological angiogenesis / 中华实验眼科杂志

ABSTRACT

The pathological growth of retinal cells and ocular pathologic angiogenesis can be seen in a variety of eye diseases,which seriously affect the visual acuity of patients.The Hedgehog signal pathway has been demonstrated to be involved in the development of retinal ganglion cells,amacrine cells,cone cells and rod cells,Müller glial cells and retinal pigment epithelial cells.This paper discusses the function of Hedgehog signal pathway in the development of retinal cells and ocular pathologic angiogenesis,which may provide a new therapeutic target for retinal and ocular vascular diseases.