The clinical effect of live Bacillus Subtilis and Enterococcus Faecium granules combined with blue light irradiation in the treatment of neonatal jaundice / 中国基层医药

ABSTRACT

Objective To explore the clinical effect of live Bacillus Subtilis and Enterococcus Faecium granulescombined with blue light irradiation in the treatment of neonatal jaundice.Methods 90 patients with neonatal jaundice were randomly divided into control group and observation group.The control group received the blue light treatment,the observation group was given blue light irradiation combined with live Bacillus Subtilis and Enterococcus Faecium granules treatment,the patients were treated for 7 days.The clinical efficacy,serum bilirubin and main indicators of complex constant time were observed in the two groups.Results After treatment,the total effective rate of the observation group was 95.6％,which of the control group was 68.9％,the difference was statistically significant (x2 =5.473,P ＜ O.05).After treatment for 1 day,3 days,7 days,the serum bilirubin values of the observation group were (185.6 ± 25.1) μmol/L,(136.7 ± 19.1) μmol/L,(82.1 ± 10.3) μmol/L,respectively,which of the control group were (205.3 ± 26.4) μmol/L,(184.1 ± 20.3) μmol/L,(128.4 ± 16.7) μmol/L,the differences between the two groups were statistically significant (t =3.628,11.408,15.829,all P ＜ 0.05).The recovery time of serum bilirubin in the observation group was (7.1 ± 2.4) d,which of the control group was (12.9 ±3.1) d,there was significant difference between the two groups (t =9.924,P ＜ 0.05).The hospitalization time of observation group was (3.5 ± 1.1) d,which of the control group was (5.8 ± 1.5) d,the difference between the two groups was statistically significant (t =8.295,P ＜ 0.05).Conclusion Live Bacillus Subtilis and Enterococcus Faecium granules combined with blue light irradiation in the treatment of neonatal jaundice is helpful to improve the clinical efficacy,reduce the treatment time and improve the clinical symptoms.