Diagnostic Value of C-reactive Protein in Complicated Appendicitis
Journal of the Korean Society of Coloproctology
;
: 122-126, 2011.
Article
Dans Anglais
| WPRIM
| ID: wpr-66806
ABSTRACT
PURPOSE:
Early detection of appendicitis has increased due to development of computed tomography and ultrasonography, yet we are frequently meeting complicated appendicitis, including perforation, abscess and a gangrenous appendicitis due to delayed diagnosis. For that reason, we want to evaluate predictive factors for the complicated appendicitis.METHODS:
A total of 128 patients with appendicitis, after 13 patients with a duration of under 12 hours and 15 patients with pathological non-appendicitis were excluded from 156 patients, who visited Kwangju Christian Hospital from November 2008 to November 2010 were retrospectively reviewed.RESULTS:
There were 62 patients (48.3%) with simple appendicitis and 66 patients (51.7%) with complicated appendicitis. In univariate analysis, age (P < 0.001), C-reactive protein (P < 0.001) and the diameter of the appendix (P = 0.006), were found to be significant. Multivariate analysis demonstrated that C-reactive protein was an independent predictor for complicated appendicitis (odds ratio, 1.371; 95% confidence interval, 1.155 to 1.628; P < 0.001). The cut-off value of C-reactive protein was set at 7.05 mg/dL by using receiver operating characteristic curve (0.805; sensitivity, 57.6%; specificity, 98.3%).CONCLUSION:
This study suggests that if C-reactive protein is above 7.05 mg/dL, immediate and proper management should be performed due to a high probability of complicated appendicitis, especially in young children or elderly patients who frequently present with vague symptoms.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Appendicite
/
Appendice vermiforme
/
Protéine C-réactive
/
Analyse multifactorielle
/
Études rétrospectives
/
Courbe ROC
/
Sensibilité et spécificité
/
Abcès
/
Retard de diagnostic
Type d'étude:
Etude diagnostique
/
Étude observationnelle
/
Étude pronostique
/
Étude de dépistage
Limites du sujet:
Adulte très âgé
/
Enfant
/
Humains
langue:
Anglais
Texte intégral:
Journal of the Korean Society of Coloproctology
Année:
2011
Type:
Article
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