Frequency and Associated Factors of Generalized Bone Loss in Premenopausal Early Rheumatoid Arthritis / 대한류마티스학회지
The Journal of the Korean Rheumatism Association
;
: 50-57, 2002.
Article
Dans Coréen
| WPRIM
| ID: wpr-66826
ABSTRACT
OBJECTIVE:
To investigate frequency and associated factors of generalized bone loss in patients with premeonpausal early rheumatoid arthritis (RA)who had not been treated with corticosteroid.METHODS:
We measured bone mineral density (BMD)of lumbar spine and hip by dual energy X-ray absorptiometry (DEXA,Hologic QDR 4500)and investigated clinical;age,disease duration,numbers of tender and swollen joint,and laboratory;erythrocyte sedimentation rate (ESR),C-reactive protein (CRP)and rheumatoid factor (RF),variables in patients with premenopausal early RA who had not been treated with corticosteroid,consecutively.Generalized bone loss was defined as T score less than -1,and clinical and laboratory variables were analyzed for generalized bone loss.RESULTS:
In 41 patients with premenopausal early RA (age;38 +/-8 years, duration of disease 8 +/-6 months),the frequency of generalized bone loss in lumbar spine and hip were 35%and 46%.In multivariate logistic regression analysis,elevated CRP level was significantly associated with generalized bone loss in lumbar spine and femur neck.CONCLUSIONS:
In patients with premenopausal early RA,elevated CRP level was associated with generalized bone loss of lumbar spine and femur neck.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Polyarthrite rhumatoïde
/
Facteur rhumatoïde
/
Rachis
/
Absorptiométrie photonique
/
Densité osseuse
/
Modèles logistiques
/
Préménopause
/
Col du fémur
/
Hanche
Type d'étude:
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Humains
langue:
Coréen
Texte intégral:
The Journal of the Korean Rheumatism Association
Année:
2002
Type:
Article
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