Effects of Shensongyangxin Capsule on hemodynamics in patients with chronic heart failure complicating ventricular arrhythmia / 重庆医学

ABSTRACT

Objective To study the effect of Shensongyangxin Capsule on hemodynamics in the patients with chronic heart failure complicating ventricular arrhythmia .Methods A total of 126 patients with chronic heart failure complicating ventricular ar-rhythmia treated in this hospital from August 2013 to January 2016 were selected as the study subjects for conducting the prospec-tive study .The former 63 cases served as the observation group and the latter 63 cases as the control group .The control group were treated with conventional Western medicines .On the basis of the control group ,the observation group was auxiliarily given Shens-ongyangxin Capsule .Both groups were treated for 8 weeks .The curative effects and hemodynamics were compared between the two groups .Results The total effective rate in the control group was 85 .7% ,which was significantly lower than 96 .8% in the treat-ment group (P<0 .05) .The central artery pressure(MAP) was in the normal range before and after treatment in two groups ,the difference between the two groups had no statistical significance (P>0 .05) .The LVDd and LVDs values after treatment in the ob-servation group were significantly higher than those in the control group (P<0 .05) ,and the LVDd and LVDs values after treat-ment in the two groups were significantly higher than those before treatment (P<0 .05) .The QTcd values after treatment in the observation group and control group were significantly lower than those before treatment (P<0 .05) ,the QTcd values after treat-ment in the observation group were significantly lower than those in the control group (P< 0 .05) .Conclusion Shensonyangxin Capsule in the treatment of chronic heart failure complicating ventricular arrhythmia does not lead to the hemodynamic abnormali-ties ,promotes the heart function improvement and plays the antiarrhythmic effect and increases the curative effect .