Your browser doesn't support javascript.
loading
Preparation and Dissolution of Jieheling Dispersible Tablets / 中国药师
China Pharmacist ; (12): 517-519, 2015.
Article de Zh | WPRIM | ID: wpr-669665
Bibliothèque responsable: WPRO
ABSTRACT
Objective:To prepare Jieheling dispersible tablets and establish the dissolution determination method. Methods:The dissolution of fischeriana B in the tablets was determined by HPLC. The column was Kromasil C18(250 mm ×4.6 mm,5μm)with ace-tonitrile-water (40∶60) as the mobile phase at a flow rate of 1. 0 ml·min-1 . The detection wavelength was at 290nm. The column temperature was 30℃ and the sample size was 100 μl. Results: The linear range of fischeriana B was 0. 005-0. 057 μg ( r =0. 999 6). The average recovery was between 95% and 105%. Phosphate solution with pH of 6. 8 was used as the dissolution medi-um. Conclusion:The method is simple, accurate and specific, and can be used in the quality control of Jieheling dispersible tablets.
Mots clés
Texte intégral: 1 Indice: WPRIM langue: Zh Texte intégral: China Pharmacist Année: 2015 Type: Article
Texte intégral: 1 Indice: WPRIM langue: Zh Texte intégral: China Pharmacist Année: 2015 Type: Article