Preliminary Study on Extraction and Separation of Anti-tumor Ingredients from Fresh Gekko Swinhonis / 中国药师
China Pharmacist
;
(12): 1841-1843, 2015.
Article
Dans Chinois
| WPRIM
| ID: wpr-670121
ABSTRACT
Objective:
To study the extraction and separation of anti-tumor active ingredients from fresh Gekko swinhonis. Meth-odsThe extraction was carried out with ethanol at different concentrations by various methods. The extract was purified by HPLC after deproteinization and degreasing using a repeated freezing and thawing method. MTT was used to detect the antitumor activity of the ex-tract.Results:
The A value of extraction process groupⅢwith 85% ethanol ultrasonic extraction was (0. 548 ± 0. 045) with the high-est tumor inhibition rate, and compared with the control group, the difference was significant (P<0. 05).Conclusion:
The results of pharmacodynamics show that the optimum extraction technology is ultrasonic extraction with 85% ethanol.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
China Pharmacist
Année:
2015
Type:
Article
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