EFFECTS OF SINOMENINE ON ISOLATED GUINEA-PIG AURICLE / 西安交通大学学报(医学版)
Journal of Xi'an Jiaotong University(Medical Sciences)
;
(6)1982.
Article
Dans Chinois
| WPRIM
| ID: wpr-674495
ABSTRACT
After Sinomenine 27 ?M was given, the contractibility was decreased to 51?11% (SD) and dT/dt max to 50?14% (SD). The automaticity induced by epinephrine was inhibited. Sinomenine (2.7-270 ?M) caused a concentration-dependent prolongation in the functional period. The amplitude of contraction and the heart rate in the right auricle was also inhibited. The results indicate that sinomenine may be antogonistic to both Ca~(++) influx and inward Na~(++) current.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Journal of Xi'an Jiaotong University(Medical Sciences)
Année:
1982
Type:
Article
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