EFFECTS OF BROWN SEAWEED POLYSACCHARIDE ON LYMPHOCYTE FUNCTION AND CYTOKINES PRODUCTION / 营养学报
Acta Nutrimenta Sinica
;
(6)1956.
Article
Dans Chinois
| WPRIM
| ID: wpr-677366
ABSTRACT
Objective:
To investigate the effects of BSP on lymphocyte function and cytokines production in normal and immunosuppressed mice.Methods:
The lymphocyte proliferation response, T lymphocyte subpopulations and IL 2 production were measured after intraperitoneal injection of BSP in normal and immunosuppressed mice, and the activity of IL 1 and TNF secreted by mouse peritoneal macrophages were detected after BSP supplementation in vitro.Results:
(1)BSP〔(100 mg/(kg?d)?10 d)〕markedly improved T,B lymphocyte proliferation responses and IL 2 production in normal and immunosuppressed mice, and significantly increased the number of L 3T + 4 cells in thymus and spleen of immunosuppressed mice, and the ratio of L 3T + 4/Lyt 2 + cells was also increased.(2)BSP distinctly enhanced the activity of IL 1 and TNF production by mouse peritoneal macrophages in vitro.Conclusion:
BSP can improve the immunological function of normal and immunosuppressed mice.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Acta Nutrimenta Sinica
Année:
1956
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS