MITOCHONDRIAL DNA MICROSATELLITE INSTABILITY AND EXPRESSION OF Bcl-2 AND Bax mRNA IN GASTRIC CANCER AND ITS PRECANCEROUS LESIONS / 解放军医学杂志
Medical Journal of Chinese People's Liberation Army
;
(12)2001.
Article
Dans Chinois
| WPRIM
| ID: wpr-678639
ABSTRACT
Objective To explore the relationship between mitochondrial DNA microsatellite instability(mtMSI) and expression of Bcl 2 and Bax mRNA in gastric cancer and its precancerous lesions. Methods mtMSI and expressions of Bcl 2 and Bax mRNA were detected with PCR SSCP and RT PCR. Results Expressions of Bcl 2 mRNA in intestinal metaplasia (IM,53 3%) and dysplasia (Dys, 70%) were significantly higher than that in normal control(10%, P
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Medical Journal of Chinese People's Liberation Army
Année:
2001
Type:
Article
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