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Analgesic Effect of Yunzhi Polysaccharopeptide and Preliminary Analysis of Its Mechanism / 中成药
Chinese Traditional Patent Medicine ; (12)1992.
Article Dans Chinois | WPRIM | ID: wpr-681419
ABSTRACT

Objective:

To observe the analgesic effect of Yunzhi polysaccharopeptide (PSP) and analyze its mechanism.

Methods:

The hot plate test in mice and the tail stimulation vocalization test in rats were used.

Results:

PSP administered po at a dose of 1.0 g/kg for 7 days could produce a significant analgesic effect, which could last for more than two hours. The analgesic effect of PSP disappeared after lesion of mediobasal hypothalamus.

Conclusions:

PSP could elicit a central analgesic effect.

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) langue: Chinois Texte intégral: Chinese Traditional Patent Medicine Année: 1992 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) langue: Chinois Texte intégral: Chinese Traditional Patent Medicine Année: 1992 Type: Article