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Effects of scorpion venom active peptides on platelet aggregation, thrombosis in carotid artery and plasma 6-keto-PGF_(1?) and TXB_2 in rabbits and rats / 中成药
Chinese Traditional Patent Medicine ; (12)1992.
Article Dans Chinois | WPRIM | ID: wpr-681792
ABSTRACT

Objective:

To investigate the mechanism of scorpion venom active peptides(SVAPs) on platelet aggregation.

Methods:

Platelet aggregation in vivo and vitro was determined by turbidimetry. Carotid thrombosis model was induced by electrostimulation. The determination of 6 keto PGF 1 and TXB 2 were performed by radioimmunoassay.

Results:

SVAPs 0.125,0.25,0.5mg?ml -1 significantly inhibited the rabbit platelet aggregation triggered by thrombase 0.03u.ml -1 , ADP 10u.ml -1 in vitro( P

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Type d'étude: Étude pronostique langue: Chinois Texte intégral: Chinese Traditional Patent Medicine Année: 1992 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Type d'étude: Étude pronostique langue: Chinois Texte intégral: Chinese Traditional Patent Medicine Année: 1992 Type: Article