Effects of pulmonary artery perfusion with hypothermic protective solution on pulmonary vascular endothelial cell injury during cardiopulmonary bypass / 中华胸心血管外科杂志
Article
de Zh
| WPRIM
| ID: wpr-682126
Bibliothèque responsable:
WPRO
ABSTRACT
Objective: To evaluate the effects of hypothermic protective solution perfusion to pulmonary artery on lung vascular endothelial cell injury during cardiopulmonary bypass. Methods: 64 children with tetrogy of Fallot were randomly divided into lung protect group (n=34) and control group (n=30). The way of lung protection was to perfuse with hypothermic protective solution to pulmonary artery. Routine approach was used in control group. Plasma ET and vWF were measured. Lung biopsy specimens were obtained at end of operation in order to study histological changes of lung vascular endothelium. The expression of ICAM 1 on lung vascular endothelium was detected. Patients' hemodynamics and lung functions were monitored. Results: ET and vWF were lower in lung protect group when compared with control group at 0 hour after operation (P
Texte intégral:
1
Indice:
WPRIM
langue:
Zh
Texte intégral:
Chinese Journal of Thoracic and Cardiovascular Surgery
Année:
2003
Type:
Article